Articolo in rivista

Glatiramer Acetate modulates ion channels expression and calcium homeostasis in B cell of patients with relapsing-remitting multiple sclerosis

To investigate the effects of Glatiramer Acetate (GA) on B cells by an integrated computational and experimental approach. GA is an immunomodulatory drug approved for the treatment of multiple sclerosis (MS). GA effect on B cells is yet to be fully elucidated. We compared transcriptional profiles…

Multi-scale Simulation of T Helper Lymphocyte Differentiation

The complex differentiation process of the CD4+ T helper lymphocytes shapes the form and the range of the immune response to different antigenic challenges. Few mathematical and computational models have addressed this key phenomenon. We here present a multiscale approach in which two different…

Lagrangian Properties of Particles in Turbulence

The Lagrangian description of turbulence is characterized by a unique con- ceptual simplicity and by an immediate connection with the physics of dis- persion and mixing. In this article, we report some motivations behind the Lagrangian description of turbulence and focus on the statistical…

Benchmarking multi-GPU applications on modern multi-GPU integrated systems

GPUs are very powerful computing accelerators that are often employed in single-device configuration. However, there is a steadily growing interest in using multiple GPUs in a concurrent way both to overcome the memory limitations of the single device and to further reduce execution times. Until…

Deviation of quadrupolar bodies from geodesic motion in a Kerr spacetime

The deviation from geodesic motion of the world line of an extended body endowed with multipolar structure up to the mass quadrupole moment is studied in the Kerr background according to the Mathisson-Papapetrou-Dixon model. The properties of the quadrupole tensor are clarified by identifying the…

Numerical simulations of acoustic fields on boundary-fitted grids

In this paper we propose a numerical method for the simulation of acousticfields, in presence of an obstacle in the physical domain, by finite difference solution of a two-dimensional differential model on boundary-fittedgrids. The computational process gathers the elliptic grid generation, the…

On the exit-times approach for epsilon-entropy and turbulent signals

We review a recently proposed approach to the computation of the E-entropy of a given signal based on the exit-time statistics, i.e., one codes the signal by looking at the instants when the fluctuations are larger than a given threshold, epsilon. Moreover, we show how the exit-times statistics,…

Integrated Network Analysis Identifies Fight-Club Nodes as a Class of Hubs Encompassing Key Putative Switch Genes That Induce Major Transcriptome Reprogramming during Grapevine Development

Lattice-Boltzmann simulations of repulsive particle-particle and particle-wall interactions: Coughing and choking

Shear dynamics of confined bijels

Bicontinuous interfacially jammed emulsion gels ("bijels") represent a new class of soft materials made of a densely packed monolayer of solid particles sequestered at the interface of a bicontinuous fluid. Their mechanical properties are relevant to many applications, such as catalysis, energy…