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Cyber insurance is a rapidly developing area which draws more and more attention of practitioners and researchers. Insurance, an alternative way to deal with residual risks, was only recently applied to the cyber world. The immature cyber insurance market faces a number of unique challenges on the… |
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Objective There is increasing interest in simultaneous endovascular delivery of more than one drug from a drug-loaded
stent into a diseased artery. There may be an opportunity to obtain a therapeutically desirable uptake profile of the two drugs
over time by appropriate design of the initial drug… |
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In this article we propose a mathematical model for the onset and progression of Alzheimer's disease based on transport and diffusion equations. We regard brain neurons as a continuous medium and structure them by their degree of malfunctioning. Two different mechanisms are assumed to be relevant… |
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We prove that if the exponent function p((.)) satisfies log-Holder continuity conditions locally and at infinity, then the fractional maximal operator M(alpha), 0 < alpha < n, maps L(p(.)) to L(q(.)), where 1/p(x) - 1/q(x) = alpha/n. We also prove a weak-type inequality corresponding to the… |
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The SARS-CoV-2 non-structural protein 13 (nsp13) helicase is an essential enzyme for viral replication and has been identified as an attractive target for the development of new antiviral drugs. In detail, the helicase catalyzes the unwinding of double-stranded DNA or RNA in a 5? to 3? direction… |
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We propose a hybrid tree-finite difference method in order to approximate the Heston model. We prove the convergence by embedding the procedure in a bivariate Markov chain and we study the convergence of European and American option prices. We finally provide numerical experiments that give… |
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The exploration and analysis of Web graphs has flourished in the recent past, producing a large number of relevant and interesting research results. However, the unique characteristics of the Tor network limit the applicability of standard techniques and demand for specific algorithms to explore… |
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