A MATHEMATICAL MODEL FOR THE ENHANCED CYTOPLASMIC TRANSPORT How to Get (Faster) to the Nucleus

Abstract
We consider a simple model for signal transport in the cytoplasm. Following some recent experimental evidences, the standard diffusion model is supplemented by advection operated through an attachement/detachement mechanism along microtubules. This model is given by a system of partial differential equations which are cast in different dimensions and connected by suitable exchange rules. A numerical scheme is introduced and some simulations are presented and discussed to show the performances of our model.
Anno
2011
Autori IAC
Tipo pubblicazione
Altri Autori
Dimitrio, Luna; Natalini, Roberto; Milanesi, Luciano