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The High-throughput Chromosome Conformation Capture (Hi-C) technique combines the power of the Next Generation Sequencing technologies with chromosome conformation capture approach to study the 3D chromatin organization at the genome-wide scale. Although such a technique is quite recent, many tools… |
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In refined network analysis, a compact network model is combined with distributed models for semiconductor devices in a multidimensional approach. For linear RLC networks containing diodes as distributed devices, we construct a mathematical model that joins the differential-algebraic initial-value… |
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Sex dimorphism in cell response to stress has previously been investigated by different research groups. This dimorphism could be at least in part accounted for by sex-biased expression of regulatory elements such as microRNAs (miRs). In order to spot previously unknown miR expression differences… |
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This work investigates the capability of supervised classification methods in detecting both major tissues and subcortical structures using multispectral brain magnetic resonance images. First, by means of a realistic digital brain phantom, we investigated the classification performance of various… |
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We present an analysis of the dynamics of the term structure of interest rates based on the study of the time evolution of the parameters of a variation of the Nelson-Siegel model. The results show that it is extremely difficult to find a relation between the evolution of the term structure and the… |
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Magnetoencephalography (MEG) aims at reconstructing the unknown neuroelectric activity in the brain from non-invasive measurements of the magnetic field induced by neural sources. The solution of this ill-posed, ill-conditioned inverse problem is usually dealt with using regularization techniques… |
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The equality constrained indefinite least squares problem involves the minimization of an indefinite quadratic form subject to a linear equality constraint. In this paper, we study this problem and present a numerical method that is proved to be backward stable in a strict sense, i.e., that the… |
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A mesoscopic multicomponent lattice Boltzmann model with short-range repulsion between different species and short (midranged) attractive (repulsive) interactions between like molecules is introduced. The interplay between these composite interactions gives rise to a rich configurational dynamics… |
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We present and compare some nonparametric estimation methods (wavelet and/or spline-based) designed to recover a one-dimensional piecewise-smooth regression function in both a fixed equidistant or not equidistant design regression model and a random design model. |
