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Recurrent focal neuropathy with liability to pressure palsies is a relatively frequent autosomal-dominant demyelinating neuropathy linked to peripheral myelin protein 22 (PMP22) gene deletions. The combination of PMP22 gene mutations with other genetic variants is known to cause a more severe… |
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MicroRNAs play a fundamental role in retinal development and function. To characterise the miRNome of the human retina, we carried out deep sequencing analysis on sixteen individuals. We established the catalogue of retina-expressed miRNAs, determined their relative abundance and found that a small… |
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An extended body orbiting a compact object undergoes tidal deformations by the background gravitational field. Tidal invariants built up with the Riemann tensor and their derivatives evaluated along the worldline of the body are essential tools to investigate both geometrical and physical… |
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We discuss multiscale simulations of long biopolymer translocation through wide nanopores that can ac- commodate multiple polymer strands. The simulations provide clear evidence of folding quantization, namely the translocation proceeds through multifolded configurations characterized by a well-… |
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The construction of a radar coordinate system about the world line of an observer is discussed. Radar coordinates for a hyperbolic observer as well as a uniformly rotating observer are described in detail. The utility of the notion of radar distance and the admissibility of radar coordinates are… |
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We numerically study the dynamics of a polydisperse double emulsion under a symmetric shear flow. We show that both dispersity and shear rate crucially affect the behavior of the innermost drops and of the surrounding shell. While at low/moderate values of shear rates, the inner drops rotate… |
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In this work, we find and test a new approximated formula (based on the thin plate approximation), for recovering small, unknown damages on the inaccessible surface of a thin conducting (aluminium) plate. We solve this inverse problem from a controlled heat flux and a sequence of temperature maps… |
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The objective of the present paper is to develop a truly functional
Bayesian method specifically designed for time series microarray
data. The method allows one to identify differentially expressed
genes in a time-course microarray experiment, to rank them and to
estimate their expression profiles… |
