Articolo in rivista

Hydrokinetic approach to large-scale cardiovascular blood flow

We present a computational method for commodity hardware-based clinical cardiovascular diagnosis based on accurate simulation of cardiovascular blood flow. Our approach leverages the flexibility of the Lattice Boltzmann method to implementation on high-performance, commodity hardware, such as…

Analyzing the Whole Transcriptome by RNA-Seq Data: The Tip of the Iceberg

Simulations of Complex Fluids by Mixed Lattice Boltzmann - Finite Difference Methods

We present the numerical results of simulations of complex fluids under shear flow. We employ a mixed approach which combines the lattice Boltzmann method for solving the Navier-Stokes equation and a finite difference scheme for the convection-diffusion equation. The evolution in time of shear…

Traveling Band Solutions in a System Modeling Hunting Cooperation

A classical Lotka-Volterra model with the logistical growth of prey-and-hunting coopera- tion in the functional response of predators to prey was extended by introducing advection terms, which included the velocities of animals. The effect of velocity on the kinetics of the problem was analyzed. In…

On the numerical solution of a nonlocal boundary value problem

We study a nonlinear boundary value problem involving a nonlocal (integral) operator in the coefficients of the unknown function. Provided sufficient conditions for the existence and uniqueness of the solution, for its approximation, we propose a numerical method consisting of a classical…

The farther the better: investigating how distance from human self affects the propensity of a peptide to be presented on cell surface by MHC class I molecules, the case of Trypanosoma cruzi.

More than twenty years ago the reverse vaccinology paradigm came to light trying to design new vaccines based on the analysis of genomic information in order to select those pathogen peptides able to trigger an immune response. In this context, focusing on the proteome of Trypanosoma cruzi, we…

On the semigroup of standard symplectic matrices and its applications

A matrix Z ? R2n×2n is said to be in the standard symplectic form if Z enjoys a block LU-decomposition in the sense of A 0 -H I Z = I G 0 AT , where A is nonsingular and both G and H are symmetric and positive definite in Rn×n. Such a structure arises naturally in the discrete algebraic Riccati…

Topological Singularities in Periodic Media: Ginzburg-Landau and Core-Radius Approaches

We describe the emergence of topological singularities in periodic media within the Ginzburg-Landau model and the core-radius approach. The energy functionals of both models are denoted by E, where ? represent the coherence length (in the Ginzburg-Landau model) or the core-radius size (in the core-…

Numerical approximation of nonhomogeneous boundary conditions on networks for a hyperbolic system of chemotaxis modeling the Physarum dynamics

Many studies have shown that Physarum polycephalum slime mold is able to find the shortest path in a maze. In this paper we study this behavior in a network, using a hyperbolic model of chemotaxis. Suitable transmission and boundary conditions at each node are considered to mimic the behavior of…

A model of ischemia-induced neuroblast activation in the adult subventricular zone

We have developed a rat brain organotypic culture model, in which tissue slices contain cortex-subventricular zone-striatum regions, to model neuroblast activity in response to in vitro ischemia. Neuroblast activation has been described in terms of two main parameters, proliferation and migration…