Articolo in rivista

Asymptotic-Preserving and Well-Balanced schemes for the 1D Cattaneo model of chemotaxis movement in both hyperbolic and diffusive regimes

Heat transfer in FitzHugh-Nagumo models

An extended FitzHugh-Nagumo model coupled with dynamical heat transfer in tissue, as described by a bioheat equation, is derived and confronted with experiments. The main outcome of this analysis is that traveling pulses and spiral waves of electric activity produce temperature variations on the…

An S-System Parameter Estimation Method (SPEM) for Biological Networks

Advances in experimental biology, coupled with advances in computational power, bring new challenges to the interdisciplinary field of computational biology. One such broad challenge lies in the reverse engineering of gene networks, and goes from determining the structure of static networks, to…

A coupled lattice Boltzmann-Multiparticle collision method for multi-resolution hydrodynamics

In this work we discuss the coupling of two mesoscopic approaches for fluid dynamics, namely the lattice Boltzmann method (LB) and the multiparticle collision dynamics (MPCD) [20] to design a new class of flexible and efficient multiscale schemes based on a dual representation of the fluid…

Bayesian models for the analysis of multisample time-course micro-array experiments

In this paper we present a functional Bayesian method for detecting genes which are temporally differentially expressed between several conditions. We identify the nature of differential expression (e.g., gene is differentially expressed between the first and the second sample but is not…

Numerical study of an evolutive model for magnetostrictive materials

Rational QZ Steps with perfect shifts

In this paper we analyze the stability of the problem of performing a rational QZ$step with a shift that is an eigenvalue of a given regular pencil H-lambda K in unreduced Hessenberg-Hessenberg form. In exact arithmetic, the backward rational QZ step moves the eigenvalue to the top of the pencil,…

Multilevel parallelism for the exploration of large-scale graphs

We present the most recent release of our parallel implementation of the BFS and BC algorithms for the study of large scale graphs. Although our reference platform is a high-end cluster of new generation NVIDIA GPUs and some of our optimizations are CUDA specific, most of our ideas can be applied…

L-Proline Induces a Mesenchymal-like Invasive Program in Embryonic Stem Cells by Remodeling H3K9 and H3K36 Methylation

Metabolites are emerging as key mediators of crosstalk between metabolic flux, cellular signaling, and epigenetic regulation of cell fate. We found that the nonessential amino acid L-proline (L-Pro) acts as a signaling molecule that promotes the conversion of embryonic stem cells into mesenchymal-…

Lattice-Boltzmann simulation of dense nanoflows: a comparison with molecular dynamics and Navier-Stokes solutions,