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We present the results obtained by using an evolution of our CUDA-based solution for the exploration, via a breadth first search, of large graphs. This latest version exploits at its best the features of the Kepler architecture and relies on a combination of techniques to reduce both the number of… |
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An extended FitzHugh-Nagumo model coupled with dynamical heat transfer in tissue, as described by a
bioheat equation, is derived and confronted with experiments. The main outcome of this analysis is that
traveling pulses and spiral waves of electric activity produce temperature variations on the… |
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Mathematical models have the potential to contribute to design and evaluate the infectivity spreading and growth of human immunodeficiency virus (HIV). Providing a better understanding of the dynamics of HIV infection in vivo and the immune system interactions with the virus can improve the… |
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In this paper we present a functional Bayesian method for detecting genes which are temporally differentially expressed between several conditions. We identify the nature of differential expression (e.g., gene is differentially expressed between the first and the second sample but is not… |
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The theoretical understanding of Gartner's "hype curve" is an interesting open question in deciding the strategic actions to adopt in presence of an incoming technology. In order to describe the hype behaviour quantitatively, we propose a mathematical approach based on a rate equation, similar to… |
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Amino acids (AAs) are well known to be involved in the regulation of glucose metabolism and, in particular, of insulin secretion. However, the effects of different AAs on insulin release and kinetics have not been completely elucidated. The aim of this study was to propose a mathematical model that… |
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Metabolites are emerging as key mediators of crosstalk between metabolic flux, cellular signaling, and epigenetic regulation of cell fate. We found that the nonessential amino acid L-proline (L-Pro) acts as a signaling molecule that promotes the conversion of embryonic stem cells into mesenchymal-… |
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Growth in static and controlled environments such as a Petri dish can be used to study the spatial population dynamics of microorganisms. However, natural populations such as marine microbes experience fluid advection and often grow up in heterogeneous environments. We investigate a generalized… |
