Abstract
We construct a population dynamics model of the competition among
immune system cells and generic tumor cells. Then, we apply the theory of optimal
control to find the optimal schedule of injection of autologous dendritic cells used
as immunotherapeutic agent.
The optimization method works for a general ODE system and can be applied
to find the optimal schedule in a variety of medical treatments that have been
described by a mathematical model.
Anno
2006
Autori IAC
Tipo pubblicazione
Altri Autori
Castiglione F., Piccoli B.
Editore
Pergamon,
Rivista
Bulletin of mathematical biology (Print)