Modeling contact inhibition of growth: Traveling waves

Abstract
We consider a simplified 1-dimensional PDE-model describing the effect of contact inhibition in growth processes of normal and abnormal cells. Varying the value of a significant parameter, numerical tests suggest two different types of contact inhibition between the cell populations: the two populations move with constant velocity and exhibit spatial segregation, or they stop to move and regions of coexistence are formed. In order to understand the different mechanisms, we prove that there exists a segregated traveling wave solution for a unique wave speed, and we present numerical results on the ``stability" of the segregated waves. We conjecture the existence of a non-segregated standing wave for certain parameter values.
Anno
2013
Autori IAC
Tipo pubblicazione
Altri Autori
M. Bertsch, M. Mimura, T. Wakasa
Editore
American Institute of Mathematical Sciences
Rivista
Networks and heterogeneous media